Hi Naveen,
When you need to stop the scenario then best practice is to stop the sender channel or inactivate the sender channel.
For current situation you can go to pimon --> Message monitoring filter the message with your sender interface, sender service and receive interface. Then cancel the message from monitoring window.
refer the below page
https://help.sap.com/saphelp_nwpi71/helpdata/en/45/c9c6c57e745708e10000000a114a6b/content.htm
